ABSTRACT
Aim. The paper aims to assess the prospects for the use of encapsulation technologies for improving bioavailability and bioactivity of plant antioxidants;to assess the prospects for the use of the materials obtained in the regulation of redox homeostasis in athletes and the reduction of SARS-CoV-2 complications. Materials and methods. Taxifolin and rutin in their original and encapsulated forms were used as plant antioxidants. Encapsulation was performed by gelatin pectin complex coacervation and conjugation to beta-cyclodextrin. The effectiveness of encapsulation technologies was assessed with the data of antioxidant activity (DPPH method, %) and bioavailability and bioactivity indices (in vitro digestion model). Results. It was found that encapsulated complexes of taxifolin and rutin were characterized by higher values of bioavailability and bioactivity. According to these findings it is possible to assume that encapsulated complexes have higher effectiveness in terms of antioxidant delivery. Conclusion. The results obtained confirm high effectiveness of the abovementioned polyphenol complexes in the regulation of redox homeostasis in athletes and the reduction of risk of oxidative stress and SARS-CoV-2 complications.
ABSTRACT
The proposed study was focused on the search for the effective method of post-COVID rehabilitation by means of Pilates training and myofascial release. Materials and methods. Fifteen females took part in the study in December 2020. Participants were divided into experimental (n = 9) and control (n = 6) groups. Severity of COVID infection varied within mild to severe stages. 7 participants had 5 to 25 % lung damage. Anthropometric measurements (body length, body weight, chest excursion) and spirometry data (vital capacity, forced vital capacity) were obtained, which demonstrated a decrease in external respiration in terms of expiratory force, maximal breathing capacity and the Tiffeneau index. For a month, the experimental group performed daily breathing exercises and exercises to improve chest mobility and respiratory muscles. These exercises were accompanied by myofascial release. Results. The proposed method of rehabilitation with the elements of Pilates training and myofascial release allowed to significantly improve pulmonary function (expiratory force, maximal breathing capacity and the Tiffeneau index) in the experimental group. No significant changes were recorded in the control group. Conclusion. Pilates training and myofascial release demonstrated their effectiveness and were recommended for post-COVID rehabilitation.